
The Neurologic Stress & Recovery Index (NSRI) measures your brain’s capacity to handle surgery—and identifies what you can strengthen before your procedure. Take the assessment. Know your numbers. Protect your brain.
Before surgery, your medical team runs blood work, checks your heart, and reviews your medications.
But there’s one organ no one evaluates—the one anesthesia affects most directly.
Your brain.
Standard preoperative screening misses invisible, modifiable neurologic risks—the very factors that determine whether your brain bounces back from surgery or struggles to recover.
Anesthesia isn’t just something that puts you to sleep.
It’s a neurologic stress event.
And your outcome depends less on the drugs used and more on the state of your brain before exposure.
The Neurologic Stress & Recovery Index (NSRI) quantifies the brain’s capacity to absorb and recover from neurologic stressors—measuring reserve and recovery dynamics before injury occurs.
In plain terms? The NSRI measures two things:
RESERVE
How much neurologic stress can your brain absorb before function starts to degrade?
RECOVERY
How quickly and completely does your brain return to baseline after stress exposure?
This isn’t a personality quiz or a wellness score. The NSRI is a clinical-grade assessment backed by 75+ peer-reviewed studies, built by a Certified Anesthesiologist Assistant who saw firsthand what standard screening misses.
The NSRI evaluates five interconnected domains that determine how your brain responds to the stress of surgery and anesthesia.
Each domain is scored individually so you know exactly where you’re strong—and where targeted support can make a real difference.
Cardiometabolic Health
Your heart, blood vessels, and metabolic system form the supply chain for your brain. When these are compromised, your brain’s fuel and oxygen delivery is reduced—limiting its ability to recover under stress.
Medication & Pain Burden
Certain medications quietly deplete brain resilience. Anticholinergic drugs, sedatives, and chronic opioid use can silently reduce your cognitive reserve margin—the exact margin your brain needs during surgery.
Sleep & Circadian Health
Restorative sleep is how your nervous system shifts into recovery mode. Disrupted sleep before surgery is one of the strongest modifiable predictors of post-operative cognitive complications.
Lifestyle Factors
Physical activity, nutrition, hydration, and alcohol patterns directly impact your brain’s stress-recovery capacity. These are among the most actionable factors you can change before your procedure.
Brain & Social Health
Cognitive engagement, sensory health, social connection, and emotional wellbeing form your brain’s support network. Isolation and untreated mood disruption amplify neurologic vulnerability.
After completing the NSRI, you’ll receive a detailed report showing exactly where your brain stands—and what you can do about it:
Your overall NSRI score with a clear resilience band (Green, Yellow, Orange, or Red)
Individual scores across all 5 domains so you can see exactly where you’re strong and where you’re vulnerable
Your top 2 priority areas—the domains where targeted optimization will have the greatest impact
A personalized “What to Tell Your Care Team” script you can bring to your next appointment
Age-stratified interpretation—because the same score means different things at different life stages
You have surgery coming up and want to know what you can do now to protect your cognitive function
You’ve been through surgery before and experienced brain fog, confusion, or personality changes that no one warned you about
You’re a caregiver preparing a loved one (especially a parent or grandparent) for a procedure
You’re a health-conscious person who wants a baseline measurement of your brain’s stress-recovery capacity—even without surgery on the horizon
You’re a practitioner looking for an evidence-based tool to assess perioperative brain resilience in your patients

Sandra, PA-C, CAA, has spent years in the operating room as a Certified Anesthesiologist Assistant. She watched patients go under anesthesia every day—and saw what standard preoperative screening was missing.
Patients with undetected neurologic vulnerabilities were waking up confused, foggy, or fundamentally changed—and no one had measured the factors that predicted it.
So she built the NSRI: the first pre-surgical assessment framework that quantifies brain reserve and recovery dynamics, backed by 75+ peer-reviewed studies. Not as an outsider criticizing the system—but as a specialty insider filling a critical gap in perioperative care.
The full assessment takes 16–22 minutes. Most people complete it in under 20 minutes. You’ll answer questions across five domains of brain resilience, plus relevant medical history. The assessment uses smart conditional logic—you only see questions that apply to you.
No. The NSRI is a pre-stressor optimization tool, not a diagnostic instrument. It identifies modifiable neurologic reserve factors and generates personalized priority areas. Your results should be discussed with your healthcare provider as part of your surgical preparation.
We’re in an early-access launch period. The full NSRI assessment is available at no cost for a limited time so we can serve as many pre-surgical patients as possible and continue refining the tool with real-world data. This won’t last forever—take advantage while it’s available.
Most brain health tools measure wellness, happiness, or cognitive performance at rest. The NSRI is the only assessment designed specifically to quantify how your brain will respond to a defined neurologic stressor like surgery and anesthesia. It measures stress tolerance, not baseline function—and it’s built on 75+ peer-reviewed studies.
Absolutely. The NSRI provides a valuable baseline measurement of your brain’s stress-recovery capacity. Many people discover modifiable factors they didn’t know were depleted. And if surgery ever enters the picture, you’ll already have a head start on optimization.
Yes. Your responses are confidential and never shared with third parties. Your results are for you and your care team—no one else.
Your report includes a personalized “What to Tell Your Care Team” script. Bring this to your next appointment—it gives your surgical team actionable information they wouldn’t otherwise have. The report also highlights your top priority areas with guidance on what can be strengthened.